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Sheryl E Koch Selected Research

Probenecid (Benemid)

1/2020Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy.
1/2018Probenecid Improves Cardiac Function in Patients With Heart Failure With Reduced Ejection Fraction In Vivo and Cardiomyocyte Calcium Sensitivity In Vitro.
6/2013Targeting TRPV1 and TRPV2 for potential therapeutic interventions in cardiovascular disease.
5/2013Probenecid as a noninjurious positive inotrope in an ischemic heart disease murine model.

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Sheryl E Koch Research Topics

Disease

5Hypertrophy
01/2021 - 05/2003
4Cardiomyopathies (Cardiomyopathy)
01/2020 - 09/2003
2Reperfusion Injury
11/2021 - 06/2013
2Pain (Aches)
11/2021 - 07/2009
2Fibrosis (Cirrhosis)
01/2021 - 11/2017
2Cardiomegaly (Heart Hypertrophy)
01/2021 - 08/2002
2Heart Failure
01/2020 - 01/2018
2Gout
01/2020 - 07/2012
2Ischemia
06/2013 - 08/2006
1Carcinoid Tumor (Carcinoid)
11/2017
1Disease Progression
11/2017
1Neuroendocrine Tumors (Neuroendocrine Tumor)
11/2017
1Primitive Neuroectodermal Tumors (PNET)
11/2017
1Neoplasms (Cancer)
11/2017
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
01/2017
1Cicatrix (Scar)
11/2014
1Myocardial Ischemia (Ischemic Heart Diseases)
05/2013
1Infarction (Infarctions)
05/2013
1Cardiovascular Diseases (Cardiovascular Disease)
02/2011
1Sleep Wake Disorders
07/2009
1Epilepsy (Aura)
07/2009
1Hypotension (Low Blood Pressure)
09/2003
1Iron Overload
09/2003
1Atrial Remodeling
05/2003

Drug/Important Bio-Agent (IBA)

4Probenecid (Benemid)FDA LinkGeneric
01/2020 - 05/2013
2Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2017
2CalciumIBA
01/2018 - 05/2003
2Adrenergic Agents (Adrenergic Drugs)IBA
01/2017 - 08/2002
1Lidocaine (Xylocaine)FDA LinkGeneric
11/2021
1Polychlorinated Dibenzodioxins (TCDD)IBA
01/2021
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2020
1EverolimusFDA Link
11/2017
1Phosphotransferases (Kinase)IBA
11/2017
1CC-223IBA
11/2017
1MTOR InhibitorsIBA
11/2017
1Sirolimus (Rapamycin)FDA Link
11/2017
1RNA (Ribonucleic Acid)IBA
11/2017
1AngiotensinsIBA
01/2017
1Capsaicin (Zostrix)FDA Link
06/2013
1Neurotransmitter Agents (Neurotransmitter)IBA
02/2011
1Calcium Channels (Calcium Channel)IBA
02/2011
1Gabapentin (Neurontin)FDA LinkGeneric
07/2009
1alpha- cyano- (3,4- dihydroxy)- N- benzylcinnamideIBA
08/2006
1Amlodipine (Norvasc)FDA LinkGeneric
09/2003
1Verapamil (Calan)FDA LinkGeneric
09/2003
1IronIBA
09/2003
1CationsIBA
09/2003

Therapy/Procedure

4Therapeutics
01/2020 - 07/2012
1Ligation
11/2014